Wheezing 
Etiology 
Obstructive Lung Disease (see Obstructive Lung Disease , [[Obstructive Lung Disease]]) 
Tracheobronchial Central Airway Obstruction (see Central Airway Obstruction , [[Central Airway Obstruction]]) 
Tracheobronchial Infection 
Tracheobronchial Neoplasm 
Primary Tracheobronchial Tumor 
Acinar Cell Carcinoma (see Acinar Cell Carcinoma , [[Acinar Cell Carcinoma]]) 
Adenoid Cystic Carcinoma (see Adenoid Cystic Carcinoma , [[Adenoid Cystic Carcinoma]]) 
Bronchial Adenoma (see Bronchial Adenoma , [[Bronchial Adenoma]]) 
Bronchial Cystadenoma (see Bronchial Cystadenoma , [[Bronchial Cystadenoma]]) 
Bronchial Carcinoid (see Bronchial Carcinoid , [[Bronchial Carcinoid]]) 
Carcinosarcoma (see Carcinosarcoma , [[Carcinosarcoma]]) 
Chemodectoma (see Chemodectoma , [[Chemodectoma]]) 
Chondroma (see Chondroma , [[Chondroma]]) 
Epithelial-Myoepithelial Carcinoma (see Epithelial-Myoepithelial Carcinoma , [[Epithelial-Myoepithelial Carcinoma]]) 
Fibroma (see Fibroma , [[Fibroma]]) 
Fibrous Histiocytoma or Xanthoma (see Fibrous Histiocytoma or Xanthoma , [[Fibrous Histiocytoma or Xanthoma]]) 
Glomus Tumor (see Glomus Tumor , [[Glomus Tumor]]) 
Granular Cell Myoblastoma (see Granular Cell Myoblastoma , [[Granular Cell Myoblastoma]]) 
Hamartoma (see Hamartoma , [[Hamartoma]]) 
Inflammatory Tracheobronchial Papilloma (see Inflammatory Tracheobronchial Papilloma , [[Inflammatory Tracheobronchial Papilloma]]) 
Leiomyoma (see Leiomyoma , [[Leiomyoma]]) 
Lipoma (see Lipoma , [[Lipoma]]) 
Lung Cancer (see Lung Cancer , [[Lung Cancer]]): common etiology 
Lymphomatoid Granulomatosis (see Lymphomatoid Granulomatosis , [[Lymphomatoid Granulomatosis]]) 
Malignant Myoepithelioma (see Malignant Myoepithelioma , [[Malignant Myoepithelioma]]) 
Mucoepidermoid Carcinoma (see Mucoepidermoid Carcinoma , [[Mucoepidermoid Carcinoma]]) 
Mucoid Pseudotumor (see Mucoid Pseudotumor , [[Mucoid Pseudotumor]]) 
Multiple Laryngeal Papillomatosis (see Multiple Laryngeal Papillomatosis , [[Multiple Laryngeal Papillomatosis]]) 
Myxoma (see Myxoma , [[Myxoma]]) 
Neurofibroma (see Neurofibroma , [[Neurofibroma]]) 
Oncocytic Carcinoma 
Papillary Cystadenocarcinoma 
Plasma Cell Granuloma (see Plasma Cell Granuloma , [[Plasma Cell Granuloma]]) 
Primary Pulmonary Hodgkin’s Disease (see Primary Pulmonary Hodgkins Disease , [[Primary Pulmonary Hodgkins Disease]]) 
Primary Pulmonary Lymphoma (see Primary Pulmonary Lymphoma , [[Primary Pulmonary Lymphoma]]) 
Primary Pulmonary Melanoma (see Primary Pulmonary Melanoma , [[Primary Pulmonary Melanoma]]) 
Primary Pulmonary Sarcoma (see Primary Pulmonary Sarcoma , [[Primary Pulmonary Sarcoma]]) 
Sebaceous Carcinoma (see Sebaceous Carcinoma , [[Sebaceous Carcinoma]]) 
Solitary Tracheobronchial Papilloma (see Solitary Tracheobronchial Papilloma , [[Solitary Tracheobronchial Papilloma]]) 
Tracheal Chondrosarcoma (see Chondrosarcoma , [[Chondrosarcoma]]) 
Tracheal Squamous Cell Cancer (see Tracheal Squamous Cell Cancer , [[Tracheal Squamous Cell Cancer]]) 
 
Endobronchial Metastases  (see also Lung Metastases-Endobronchial , [[Lung Metastases-Endobronchial]])
Breast Cancer (see Breast Cancer , [[Breast Cancer]]) 
Cervical Cancer (see Cervical Cancer , [[Cervical Cancer]]) 
Chronic Lymphocytic Leukemia (CLL) (see Chronic Lymphocytic Leukemia , [[Chronic Lymphocytic Leukemia]]) 
Colorectal Cancer (see Colorectal Cancer , [[Colorectal Cancer]]) 
Endometrioma (see Endometrioma , [[Endometrioma]]) 
Esophageal Cancer (see Esophageal Cancer , [[Esophageal Cancer]]) 
Germ Cell Tumor (see Germ Cell Tumor , [[Germ Cell Tumor]]) 
Head and Neck Cancer (see Head and Neck Cancer , [[Head and Neck Cancer]]) 
Hodgkin’s Disease (see Hodgkins Disease , [[Hodgkins Disease]]) 
Kaposi Sarcoma (see Kaposi Sarcoma , [[Kaposi Sarcoma]]) 
Lymphoma (see Lymphoma , [[Lymphoma]]) 
Melanoma (see Melanoma , [[Melanoma]]) 
Ovarian Cancer (see Ovarian Cancer , [[Ovarian Cancer]]) 
Plasmacytoma (see Multiple Myeloma , [[Multiple Myeloma]]) 
Renal Cell Cancer (see Renal Cancer , [[Renal Cancer]]) 
Sarcoma 
Testicular Cancer (see Testicular Cancer , [[Testicular Cancer]]) 
Thymic Carcinoma (see Thymoma , [[Thymoma]]) 
Thyroid Cancer (see Thyroid Cancer , [[Thyroid Cancer]]) 
Urothelial Cell Carcinoma (Transitional Cell Carcinoma) (see Urothelial Cell Carcinoma , [[Urothelial Cell Carcinoma]])
 
 
 
Extrinsic Tracheobronchial Compression 
Enlarged Pulmonary Artery 
Tetralogy of Fallot (see Tetralogy of Fallot , [[Tetralogy of Fallot]]) 
Transposition of Great Vessles with Ventricular Septal Defect 
 
Granulomatous Mediastinitis and Fibrosing Mediastinitis  (see Granulomatous Mediastinitis and Fibrosing Mediastinitis , [[Granulomatous Mediastinitis and Fibrosing Mediastinitis]])Mediastinal Mass  (see Mediastinal Mass , [[Mediastinal Mass]]): extrinsic compression of tracheobronchial airways
Bulky Mediastinal or Peribronchial Lymphadenopathy
Cancer 
Hodgkin’s Disease (see Hodgkin’s Disease , [[Hodgkins Disease]]) 
Lymphoma (see Lymphoma , [[Lymphoma]]) 
Tuberculosis (see Tuberculosis , [[Tuberculosis]]): involvement of mediastinal nodes may compress RML bronchus 
Sarcoidosis (see Sarcoidosis , [[Sarcoidosis]]) 
 
 
Mediastinal Tumor 
 
Thoracic Aortic Aneurysm (TAA)  (see Thoracic Aortic Aneurysm , [[Thoracic Aortic Aneurysm]]): extrinsic compression of tracheobronchial airwaysThyroid Cancer/Thyromegaly/Goiter  (see Goiter , [[Goiter]] and Thyroid Cancer , [[Thyroid Cancer]]) 
Other Tracheobronchial Obstructive Process 
Airway Foreign Body  (see Airway Foreign Body , [[Airway Foreign Body]])Blood Clot Bronchial Stenosis  (see Bronchial Stenosis , [[Bronchial Stenosis]])Bronchocentric Granulomatosis  (see Bronchocentric Granulomatosis , [[Bronchocentric Granulomatosis]])Broncholithiasis  (see Broncholithiasis , [[Broncholithiasis]])Bronchopulmonary Amyloidosis  (see Amyloidosis , [[Amyloidosis]])Goiter Granulation Tissue 
Airway Foreign Body 
Airway Stent 
Endotracheal Tube 
Surgical Airway Anastomosis (see Lung Transplant , [[Lung Transplant]]) 
Tracheostomy Tube (see Tracheostomy , [[Tracheostomy]]) 
 
Granulomatosis with Polyangiitis (Wegener’s Granulomatosis)  (see Granulomatosis with Polyangiitis , [[Granulomatosis with Polyangiitis]])Hunter’s Syndrome Hurler’s Syndrome Mucous Plug  (see Mucous Plug , [[Mucous Plug]])Mucoid Impaction  (see Mucoid Impaction , [[Mucoid Impaction]])Post-Extubation Tracheal Edema Post-Pneumonectomy Syndrome  (see Post-Pneumonectomy Syndrome , [[Post-Pneumonectomy Syndrome]])Post-Radiation Therapy  (see Radiation Therapy , [[Radiation Therapy]])Relapsing Polychondritis  (see Relapsing Polychondritis , [[Relapsing Polychondritis]])Saber Sheath Trachea  (see Saber Sheath Trachea , [[Saber Sheath Trachea]])Smoke Inhalation  (see Smoke Inhalation , [[Smoke Inhalation]])Toxic Fume Airway Injury Tracheal Cyst  (see Tracheal Cyst , [[Tracheal Cyst]])Tracheal Stenosis  (see Tracheal Stenosis , [[Tracheal Stenosis]])Tracheal Trauma Tracheobronchial Foreign Body  (see Airway Foreign Body , [[Airway Foreign Body]])Tracheobronchial Fracture  (see Tracheobronchial Fracture , [[Tracheobronchial Fracture]])Tracheoesophageal Fistula  (see Tracheoesophageal Fistula , [[Tracheoesophageal Fistula]])Tracheobronchomalacia  (see Tracheobronchomalacia , [[Tracheobronchomalacia]])Tracheobronchial Web Tracheobronchopathia Osteochondroplastica  (see Tracheobronchopathia Osteochondroplastica , [[Tracheobronchopathia Osteochondroplastica]]) 
 
Other Airway Obstruction 
Infection 
Drug 
Abacavir Hypersensitivity Reaction  (see Abacavir , [[Abacavir]])Angiotensin Converting Enzyme (ACE) Inhibitors  (see Angiotensin Converting Enzyme Inhibitors , [[Angiotensin Converting Enzyme Inhibitors]])Aclidinium (Tudorza Pressair)  (see Aclidinium , [[Aclidinium]])Adenosine  (see Adenosine , [[Adenosine]])Benzylisoquinolinium Neuromuscular Junction Antagonists  (see Neuromuscular Junction Antagonists , [[Neuromuscular Junction Antagonists]]): mediated via histamine release
Alcuronium 
Atracurium (Tracrium) (see Atracurium , [[Atracurium]]) 
Cisatracurium (see Cisatracurium , [[Cisatracurium]]) 
Doxacurium (see Doxacurium , [[Doxacurium]]) 
Mivacurium (see Mivacurium , [[Mivacurium]]) 
Tubocurarine 
 
Beta Blockers  (see β-Adrenergic Receptor Antagonists , [[β-Adrenergic Receptor Antagonists]])Bronchodilator Agents Which Have Been Associated with Paradoxical Bronchospasm 
Cetuximab (Erbitux)  (see Cetuximab , [[Cetuximab]])Cytokine Release Syndrome  (see Cytokine Release Syndrome , [[Cytokine Release Syndrome]]): occurs with the administration of specific monoclonal antibodies
Alemtuzumab (Campath, MabCampath, Campath-1H, Lemtrada) (see Alemtuzumab , [[Alemtuzumab]]) 
Anti-Thymocyte Globulin (ATG) (see Anti-Thymocyte Globulin , [[Anti-Thymocyte Globulin]]) 
Lenalidomide (Revlimid) (see Lenalidomide , [[Lenalidomide]]) 
Muromonab-CD3 (Orthoclone OKT3) (see Muromonab-CD3 , [[Muromonab-CD3]]) 
Oxaliplatin (Eloxatin, Oxaliplatin Medac) (see Oxaliplatin , [[Oxaliplatin]]) 
Rituximab (Rituxan) (see Anti-CD20 Therapy , [[Anti-CD20 Therapy]]) 
 
Gemcitabine  (see Gemcitabine , [[Gemcitabine]])Interferon-Alpha  (see Interferon , [[Interferon]])Paclitaxel  (see Paclitaxel , [[Paclitaxel]])Mitomycin C  (see Mitomycin , [[Mitomycin]])N-Acetylcysteine (Mucomyst, Acetadote, Fluimucil, Parvolex)  (see N-Acetylcysteine , [[N-Acetylcysteine)Nitrofurantoin  (see Nitrofurantoin , [[Nitrofurantoin]])Ocrelizumab (Ocrevus)  (see Ocrelizumab , [[Ocrelizumab]])
Epidemiology: bronchospasm may occur as a feature of infusion reaction 
 
Opiates  (see Opiates , [[Opiates]])
Paclitaxel (Taxol)  (see Paclitaxel , [[Paclitaxel]])Panitumumab (Vectibix)  (see Panitumumab , [[Panitumumab]])Rasburicase (Elitek)  (see Rasburicase , [[Rasburicase]])Ribavirin  (see Ribavirin , [[Ribavirin]])Teniposide (Vumon, VM-26)  (see Teniposide , [[Teniposide]])Trastuzumab (Herceptin)  (see Trastuzumab , [[Trastuzumab]])Vinblastine  (see Vinblastine , [[Vinblastine]])Zanamivir (Relenza)  (see Zanamivir , [[Zanamivir]]) 
Toxin 
Acetic Acid Inhalation  (see Acetic Acid , [[Acetic Acid]])Ammonia Inhalation  (see Ammonia , [[Ammonia]])Bromine Inhalation/Methyl Bromide Inhalation  (see Bromine-Methyl Bromide , [[Bromine-Methyl Bromide]])Chlorine Gas/Aerosol Inhalation  (see Chlorine , [[Chlorine]])Chloropicrin Gas Inhalation  (see Chloropicrin Gas , [[Chloropicrin Gas]])Cholinergic Intoxication  (see Cholinergic Intoxication , [[Cholinergic Intoxication]])
Cigua Toxin Poisoning (see Cigua Toxin Poisoning , [[Cigua Toxin Poisoning]]) 
Organophosphate/Carbamate Intoxication (see Organophosphates-Carbamates , [[Organophosphates-Carbamates]]) 
Scorpion Sting (see Scorpion Sting , [[Scorpion Sting]])
Associated Scorpion Species 
Centuroides Exilicauda (Sculpuratus) Centuroides Suffusus  
 
Toxic Mushrooms (see Toxic Mushrooms , [[Toxic Mushrooms]])
Associated Mushrooms 
Boletus Calopus Clitocybe Dealbata Clitocybe Illudens Inocybe Fastigiata  
 
 
Chromic Acid Inhalation  (see Chromic Acid , [[Chromic Acid]])Diborane Gas Inhalation  (see Diborane Gas , [[Diborane Gas]])Dinitrogen Tetroxide Inhalation  (see Dinitrogen Tetroxide , [[Dinitrogen Tetroxide]])Hydrofluoric Acid Inhalation  (see Hydrofluoric Acid , [[Hydrofluoric Acid]])Hydrogen Sulfide Gas Inhalation  (see Hydrogen Sulfide Gas , [[Hydrogen Sulfide Gas]])Metal Fume Fever  (see Metal Fume Fever , [[Metal Fume Fever]])Methamphetamine  (see Methamphetamine , [[Methamphetamine]])Methyl Isocyanate Inhalation  (see Methyl Isocyanate , [[Methyl Isocyanate]])Methyl Isothiocyanate Inhalation  (see Methyl Isothiocyanate , [[Methyl Isothiocyanate]])Neurotoxic Shellfish Inhalation  (see Neurotoxic Shellfish , [[Neurotoxic Shellfish]])Nitric Acid Inhalation  (see Nitric Acid , [[Nitric Acid]])Nitrogen Dioxide Inhalation  (see Nitrogen Dioxide , [[Nitrogen Dioxide]])Ozone Inhalation  (see Ozone , [[Ozone]])Phosgene Gas Inhalation  (see Phosgene Gas , [[Phosgene Gas]])Phosphine Gas Inhalation  (see Phosphine Gas , [[Phosphine Gas]])Polymer Fume Fever  (see Polymer Fume Fever , [[Polymer Fume Fever]])Smoke Inhalation  (see Smoke Inhalation , [[Smoke Inhalation]])Sulfur Dioxide Inhalation  (see Sulfur Dioxide , [[Sulfur Dioxide]])Sulfuric Acid Inhalation  (see Sulfuric Acid , [[Sulfuric Acid]])Sulfur Mustard Gas Inhalation  (see Sulfur Mustard Gas , [[Sulfur Mustard Gas]])Tear Gas Inhalation  (see Tear Gas , [[Tear Gas]])VX Nerve Agent  (see VX Nerve Agent , [[VX Nerve Agent]])Zinc Chloride Gas Inhalation (Smoke Bomb Exposure)  (see Zinc Chloride Gas , [[Zinc Chloride Gas]]) 
Pulmonary Infiltrates with Eosinophilia (PIE) Syndrome  (see Pulmonary Infiltrates with Eosinophilia , [[Pulmonary Infiltrates with Eosinophilia]])
Acute Eosinophilic Pneumonia  (see Acute Eosinophilic Pneumonia , [[Acute Eosinophilic Pneumonia]])Acute Lung Transplant Rejection (Acute Cellular Lung Transplant Rejection)  (see Acute Lung Transplant Rejection , [[Acute Lung Transplant Rejection]])Allergic Bronchopulmonary Aspergillosis (ABPA)  (see Allergic Bronchopulmonary Aspergillosis , [[Allergic Bronchopulmonary Aspergillosis]])Allergic Bronchopulmonary Candidiasis  (see Candida , [[Candida]])Bronchocentric Granulomatosis  (see Bronchocentric Granulomatosis , [[Bronchocentric Granulomatosis]])Chronic Eosinophilic Pneumonia  (see Chronic Eosinophilic Pneumonia , [[Chronic Eosinophilic Pneumonia]])Dirofilariasis  (see Dirofilariasis , [[Dirofilariasis]])Drug-Induced Pulmonary Eosinophilia  (see Drug-Induced Pulmonary Eosinophilia , [[Drug-Induced Pulmonary Eosinophilia]])Eosinophilia-Myalgia Syndrome  (see Eosinophilia-Myalgia Syndrome , [[Eosinophilia-Myalgia Syndrome]])Eosinophilic Granulomatosis with Polyangiitis (EGPA, Churg-Strauss Syndrome, Allergic Angiitis and Granulomatosis)  (see Eosinophilic Granulomatosis with Polyangiitis , [[Eosinophilic Granulomatosis with Polyangiitis]])Hypereosinophilic Syndrome  (see Hypereosinophilic Syndrome , [[Hypereosinophilic Syndrome]])Sarcoidosis  (see Sarcoidosis , [[Sarcoidosis]])Simple Pulmonary Eosinophilia (Loffler’s Syndrome)  (see Simple Pulmonary Eosinophilia , [[Simple Pulmonary Eosinophilia]])Tropical Pulmonary Eosinophilia (Occult Filariasis)  (see Tropical Pulmonary Eosinophilia , [[Tropical Pulmonary Eosinophilia]])Visceral Larva Migrans  (see Visceral Larva Migrans , [[Visceral Larva Migrans]])Other Infections 
Brucellosis (see Brucellosis , [[Brucellosis]]) 
Coccidioidomycosis (see Coccidioidomycosis , [[Coccidioidomycosis]]) 
Cryptococcosis (see Cryptococcosis , [[Cryptococcosis]]) 
Echinococcosis (see Echinococcosis , [[Echinococcosis]]) 
Histoplasmosis (see Histoplasmosis , [[Histoplasmosis]]) 
Human Immunodeficiency Virus (HIV) (see Human Immunodeficiency Virus , [[Human Immunodeficiency Virus]]) 
Mycobacterium Simiae (see Mycobacterium Simiae , [[Mycobacterium Simiae]]) 
Paragonimiasis (see Paragonimiasis , [[Paragonimiasis]]) 
Schistosomiasis (see Schistosomiasis , [[Schistosomiasis]]) 
Trichinosis (see Trichinosis , [[Trichinosis]]) 
Tuberculosis (see Tuberculosis , [[Tuberculosis]]) 
 
 
Bronchiolitis Syndrome 
Other 
Acute Pulmonary Embolism  (see Acute Pulmonary Embolism , [[Acute Pulmonary Embolism]])Air Embolism  (see Air Embolism , [[Air Embolism]])Airway Foreign Body  (see Airway Foreign Body , [[Airway Foreign Body]])Alpha-1 Antitrypsin Deficiency  (see Alpha-1 Antitrypsin Deficiency , [[Alpha-1 Antitrypsin Deficiency]])Anaphylaxis  (see Anaphylaxis , [[Anaphylaxis]])Asthma  (see Asthma , [[Asthma]])Beta Thalassemia Major  (see Thalassemias , [[Thalassemias]])Bronchiectasis  (see Bronchiectasis , [[Bronchiectasis]])Byssinosis  (see Byssinosis , [[Byssinosis]])Cardiac Asthma  (see Congestive Heart Failure , [[Congestive Heart Failure]])Cholinergic Intoxication  (see Cholinergic Intoxication , [[Cholinergic Intoxication]])Chronic Berylliosis  (see Beryllium , [[Beryllium]])Chronic Granulomatous Disease (CGD)  (see Chronic Granulomatous Disease , [[Chronic Granulomatous Disease]])Chronic Obstructive Pulmonary Disease (COPD)  (see Chronic Obstructive Pulmonary Disease , [[Chronic Obstructive Pulmonary Disease]])Combined Pulmonary Fibrosis and Emphysema  (see Combined Pulmonary Fibrosis and Emphysema , [[Combined Pulmonary Fibrosis and Emphysema]])Common Variable Immunodeficiency (CVID)  (see Common Variable Immunodeficiency , [[Common Variable Immunodeficiency]])Cystic Fibrosis (CF)  (see Cystic Fibrosis , [[Cystic Fibrosis]])Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)  (see Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia , [[Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia]])Fabry Disease  (see Fabry Disease , [[Fabry Disease]])Foreign Body Granulomatosis  (see Foreign Body Granulomatosis , [[Foreign Body Granulomatosis]])Hypocalcemia  (see Hypocalcemia , [[Hypocalcemia]])Isolated IgA Deficiency  (see Isolated IgA Deficiency , [[Isolated IgA Deficiency]])Langerhans Cell Histiocytosis  (see Langerhans Cell Histiocytosis , [[Langerhans Cell Histiocytosis]])Lymphangioleiomyomatosis (LAM)  (see Lymphangioleiomyomatosis , [[Lymphangioleiomyomatosis]])Marfan Syndrome  (see Marfan Syndrome , [[Marfan Syndrome]])Microscopic Polyangiitis  (see Microscopic Polyangiitis , [[Microscopic Polyangiitis]])Mineral Dust Airway Disease Occupational Asthma  (see Asthma-Occupational , [[Asthma-Occupational]])Post-Infection Obstructive Airways Disease Primary Ciliary Dyskinesia  (see Primary Ciliary Dyskinesia , [[Primary Ciliary Dyskinesia]])Reactive Airway Dysfunction Syndrome (RADS)  (see Reactive Airway Dysfunction Syndrome , [[Reactive Airway Dysfunction Syndrome]])Selective IgG Subclass Deficiency  (see Selective IgG Subclass Deficiency , [[Selective IgG Subclass Deficiency]])Sjogren’s Syndrome  (see Sjogrens Syndrome , [[Sjogrens Syndrome]])Swyer-James-Macleod Syndrome  (see Swyer-James-Macleod Syndrome , [[Swyer-James-Macleod Syndrome]])Tuberous Sclerosis  (see Tuberous Sclerosis , [[Tuberous Sclerosis]]) 
 
References 
The functional basis of pulmonary sounds.  Chest. 1978;73(3):399 [MEDLINE ] 
Diagnosis of bronchial asthma by clinical evaluation. An unreliable method.  Chest. 1983;84(1):42 [MEDLINE ] 
Lung sounds.  Am Rev Respir Dis. 1984;130(4):663 [MEDLINE ] 
Fundamentals of lung auscultation.  N Engl J Med. 2014;370(8):744 [MEDLINE ] 
 
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