Hantavirus Cardiopulmonary Syndrome


Epidemiology

History

Geography

Reportable Disease


Transmission/Virology

Transmission

Virology

Hantavirus Genus


Diagnosis

Serology

Nested Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) for Hantavirus

Immunohistochemical Assay for N Antigen


Clinical Manifestations

General Comments

Prodromal Phase

Cardiopulmonary Phase

General Comments

Cardiovascular Manifestations

Gastrointestinal Manifestations

Hematologic Manifestations

Pulmonary Manifestations

Renal Manifestations

Oliguric/Diuretic Phase

Convalescent Phase


Prevention


Treatment

Pharmacologic Therapy

Ribavirin (see Ribavirin, [[Ribavirin]])

Corticosteroids (see Corticosteroids, [[Corticosteroids]])

Respiratory Management

Mechanical Ventilation

Venovenous Extracorporeal Membrane Oxygenation (VV-ECMO) (see Venovenous Extracorporeal Membrane Oxygenation, [[Venovenous Extracorporeal Membrane Oxygenation]])


Prognosis


References

General

Treatment