Diltiazem (Cardizem, Tiazac, Dilt-CD)

Indications

  • Hypertension (see Hypertension, [[Hypertension]])
  • Migraine Prophylaxis (see Migraines, [[Migraines]])
  • Rate Control of AV Nodal-Mediated Arrhythmias
    • Atrial Fibrillation with Rapid Ventricular Response (see Atrial Fibrillation, [[Atrial Fibrillation]])
    • Supraventricular Tachycardia (SVT) with Rapid Ventricular Response (see Supraventricular Tachycardia, [[Supraventricular Tachycardia]])

Contraindications

Atrioventricular Heart Blocks

Hypotension (see xxxx, [[xxxx]])

  • Diltiazem Can Exacerbate Hypotension

Pharmacology

  • Non-Dihydropyridines (Benzothiazepine) Calcium Channel Blocker (see Calcium Channel Blockers, [[Calcium Channel Blockers]])
    • AV Nodal Blockade
    • xxx

Administration

  • PO:
  • IV: 5 mg bolus, then 5-15 mg/hr drip

Adverse Effects

Cardiovascular Adverse Effects

Atrioventricular Heart Blocks

Bradycardia (see Bradycardia, [[Bradycardia]])

  • May Occur

Hypotension (see Hypotension, [[Hypotension]])

  • Physiology: class effect (common to all calcium channel blockers)

Other Adverse Effects

  • xxx
  • xxx
  • xxx
  • xxx

Calcium Channel Blocker Intoxication


References

  • xxx