Calcium Chloride

Indications

  • Beta Blocker Intoxication Refractory to Glucagon and Vasopressors (see xxxx, [[xxxx]])
  • Calcium Channel Blocker Intoxication (see Calcium Channel Blockers, [[Calcium Channel Blockers]])
  • Hypocalcemia (see Hypocalcemia, [[Hypocalcemia]])

Pharmacology

  • Calcium

Administration

  • PO: not recommended (due to the development of non-anion gap metabolic acidosis)
  • IV: 1 Amp (10 mL) IV PRN
    • CaCl 1g IV (10 ml of 10% Solution) Contains 273 mg (13.6 mEq) of Elemental Calcium

Adverse Effects

Renal Adverse Effects

  • Non-Anion Gap Metabolic Acidosis (see Metabolic Acidosis-Normal Anion Gap, [[Metabolic Acidosis-Normal Anion Gap]])
    • Epidemiology: with oral administration only
    • Mechanism: calcium chloride administered orally is excreted as calcium bicarbonate (due to exchange of the chloride for bicarbonate) -> results in gastrointestinal bicarbonate loss and metabolic acidosis

Other Adverse Effects

  • xxx

References

  • xxx