Extrapyramidal Symptoms

Etiology

Metabolic

Drugs

  • Amiodarone (Cordarone) (see Amiodarone, [[Amiodarone]])
  • Metoclopramide (Reglan) (see Metoclopramide, [[Metoclopramide]])
  • Promethazine (Phenergan) (see Promethazine, [[Promethazine]])
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Clinical Manifestations

Neurologic Manifestations

  • Akathisia (see Akathisia, [[Akathisia]]): motor restlessness
  • Dystonia (see Dystonia, [[Dystonia]]): continuous spasms and muscle contractions
  • Parkinsonism (see Parkinson’s Disease, [[Parkinsons Disease]]): rigidity, bradykinesia, tremor
  • Tardive Dyskinesia (see Tardive Dyskinesia, [[Tardive Dyskinesia]]): irregular, jerky movements

Treatment

Anti-Cholinergic Agents

Dopamine Agonists

  • Pramipexole (Mirapex) (see Pramipexole, [[Pramipexole]])

References

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