Intracardiac and Extracardiac Shunt 
Intracardiac Shunt 
Atrial Septal Defect (ASD) (see Atrial Septal Defect , [[Atrial Septal Defect]]) 
L->R Shunt : normal direction of shunting in absence of pulmonary hypertension
Diagnosis 
Echocardiogram: 
Swan: step-up in SaO2 from venous SaO2 to right atrium 
 
 
R->L Shunt : occurs in cases with pulmonary hypertension
Diagnosis 
Echocardiogram: bubble study (injection of agitated saline injected into vein) reveals shunt, with rapid appearance of bubbles on left side of heart 
Swan: 
 
Clinical 
Hypoxemia (see Hypoxemia , [[Hypoxemia]]): due to blood bypassing pulmonary circulation 
 
 
 
Patent Foramen Ovale (PFO) (see Patent Foramen Ovale , [[Patent Foramen Ovale]]) 
L->R Shunt : normal direction of shunting in absence of pulmonary hypertension
Diagnosis 
Echocardiogram 
Swan: step-up in SaO2 from venous SaO2 to right atrium 
 
 
R->L Shunt : occurs in cases with pulmonary hypertension
Diagnosis 
Echocardiogram: bubble study (injection of agitated saline injected into vein) reveals shunt, with rapid appearance of bubbles on left side of heart 
Swan: 
 
Clinical 
Hypoxemia (see Hypoxemia , [[Hypoxemia]]): due to blood bypassing pulmonary circulation 
 
 
 
Ruptured Sinus of Valsalva Aneurysm (see Sinus of Valsalva Aneurysm , [[Sinus of Valsalva Aneurysm]]) 
L->R Shunt : in cases with rupture into right atrium or right ventricle
Diagnosis 
Clinical 
Dyspnea (see Dyspnea , [[Dyspnea]]): most common manifestation 
xxx 
 
 
L->L Shunt : in cases with rupture into left ventricle
 
Ventricular Septal Defect (VSD)/Ventricular Septal Rupture (see Ventricular Septal Defect , [[Ventricular Septal Defect]] and Ventricular Septal Rupture , [[Ventricular Septal Rupture]]) 
L->R Shunt : normal direction of shunting in absence of pulmonary hypertension
Diagnosis 
Echocardiogram: 
Swan: step-up in SaO2 from venous right atrium to right ventricle 
 
 
R->L Shunt : occurs in cases with pulmonary hypertension
Diagnosis 
Echocardiogram: bubble study (injection of agitated saline injected into vein) reveals shunt, with rapid appearance of bubbles on left side of heart 
Swan: 
 
Clinical 
Hypoxemia (see Hypoxemia , [[Hypoxemia]]): due to blood bypassing pulmonary circulation 
 
 
 
Extracardiac Shunt 
Hepatopulmonary Syndrome (see Hepatopulmonary Syndrome , [[Hepatopulmonary Syndrome]]) 
Diagnosis 
Echocardiogram : bubble study (injection of agitated saline injected into vein) reveals shunt, with delayed appearance of bubbles (after 3-6 cardiac cycles) on left side of heart 
Clinical 
 
References 
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