Aluminum

Exposure

  • Aluminum Pot Room Workers

Clinical Manifestations

Pulmonary Manifestations

  • Occupational Asthma (“Pot Room Asthma”) (see Asthma-Occupational, [[Asthma-Occupational]])
  • Aluminum Dust Pneumoconiosis/Interstitial Pulmonary Fibrosis (see Interstitial Lung Disease-Etiology, [[Interstitial Lung Disease-Etiology]])
    • Epidemiology
      • First reported in Germany in 1930’s
      • Most cases are associated with aluminum powder exposure or arc welding on aluminum: high levels of exposure are usually required
      • Latency: 3-15 years
    • Diagnosis
      • CXR/Chest CT: upper lobe-predominant reticular, nodular, or reticulonodular infiltrates
        • Diffuse, small, ill-defined centrilobular opacities may be seen
        • Increased lymph node attenuation seen in soft tissue windows on Chest CT
        • In advanced disease, emphysematous blebs may be seen
      • OLB: usual interstitial pneumonia-like pattern (see Usual Interstitial Pneumonia, [[Usual Interstitial Pneumonia]])
        • Pigmented macrophages around bronchovascular bundle
    • Treatment/Prognosis: usually progress despite removal from exposure
  • Granulomatous Interstitial Lung Disease (see Granulomatous Lung Disease, [[Granulomatous Lung Disease]])
    • Diagnosis
      • FOB-BAL: helper T-lymphocyte alveolitis
      • FOB-TBB: sarcoid-like epithelioid granulomas
  • Desquamative Interstitial Pneumonitis (see Desquamative Interstitial Pneumonia, [[Desquamative Interstitial Pneumonia]])
    • May occur with high levels of aluminum dust exposure
  • Pulmonary Alveolar Proteinosis (see Pulmonary Alveolar Proteinosis, [[Pulmonary Alveolar Proteinosis]])
    • May occur with high levels of aluminum dust exposure

Other Manifestations

  • xxxx

References

  • Sarcoid-like lung granulomatosis induced by aluminum dusts. Am Rev Respir Dis. 1987 Feb;135(2):493-7