Epsilon Aminocaproic Acid (Amicar)

Indications


Pharmacology

  • Anti-Fibrinolytic (see Anti-Fibrinolytics, [[Anti-Fibrinolytics]]): lysine analogue which binds to kringle domains of plasminogen, disrupting interaction between plasminogen (and plasmin) and lysine residues within fibrin
    • Tranexamic Acid (see Tranexamic Acid, [[Tranexamic Acid]]): binds plasminogen (and plasmin) 8x more avidly than the older epsilon aminocaproic acid analogue -> may exert a more potent anti-hemorrhagic effect

Administration

  • IV

Adverse Effects

Other Adverse Effects

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References

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