Dalteparin (Fragmin)

Indications

  • xxx
  • xxx

Pharmacology

  • Low Molecular Weight Heparin

Administration

  • xxx

Effect on Anticoagulation Tests

  • PT/INR: no effect
    • Dalteparin is an indirect thrombin inhibitor and should theoretically prolong the INR: however, most INR assay reagents contain heparin-binders which block the effect of heparin (or similar agents) at concentrations <1 unit/mL -> therefore, at heparin concentration of >1 unit/mL, the INR may be prolonged
  • PTT: no effect-prolonged
  • Anti-Factor Xa: prolonged

Adverse Effects

Hematologic Adverse Effects

  • xxx
  • xxx
  • xxx
  • xxx

Other Adverse Effects

  • xxx
  • xxx
  • xxx

References

  • xxx