Protein-Losing Gastroenteropathy

Epidemiology

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Etiology

Primary gastrointestinal mucosal diseases (typically ulcerative/erosive) include the following

  • Clostridium Difficile Colitis (see Clostridium Difficile, [[Clostridium Difficile]])
  • Erosions or ulcerations of the esophagus, stomach, or duodenum
  • Regional enteritis
  • Graft versus host disease
  • Mucosal-based neoplasia
  • Carcinoid syndrome
  • Idiopathic ulcerative jejunoileitis
  • Amyloidosis
  • Kaposi sarcoma
  • Protein dyscrasia
  • Ulcerative colitis
  • Neurofibromatosis (see Neurofibromatosis, [[Neurofibromatosis]])
  • Cytomegalovirus infection

Increased interstitial pressure or lymphatic obstruction leading to Protein Loss

Non-Erosive Upper Gastrointestinal Diseases

  • Burns (see Burns, [[Burns]])
  • Whipple disease
  • Connective tissue disorders
  • Acquired immunodeficiency syndrome (AIDS)
  • Enteropathy, such as angioedema (idiopathic or hereditary) and Henoch-Schönlein purpura
  • Celiac sprue
  • Tropical sprue
  • Allergic gastroenteritis
  • Eosinophilic gastroenteritis
  • Giant hypertrophic gastritis (Ménétrier disease)
  • Bacterial overgrowth
  • Intestinal parasites
  • Microscopic colitis
  • Dientamoeba fragilis

Physiology

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Diagnosis

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Clinical Manifestations

Other Manifestations

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Treatment

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References

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