Sulindac (Clinoril)


Indications


Contraindications


Pharmacology

Nonsteroidal Anti-Inflammatory Drug (NSAID) (see Nonsteroidal Anti-Inflammatory Drug)

Metabolism


Administration


Adverse Effects

Endocrinologic Adverse Effects

Drug-Induced Hyporeninemic Hypoaldosteronism (see Hypoaldosteronism)

Gastrointestinal Adverse Effects

Acute Pancreatitis (see Acute Pancreatitis): definite association with acute pancreatitis

Peptic Ulcer Disease (PUD) (see Peptic Ulcer Disease)

Hematologic Adverse Effects

Pulmonary Adverse Effects

Aspirin-Intolerant Asthma (see Asthma)

Drug-Induced Pulmonary Eosinophilia (see Drug-Induced Pulmonary Eosinophilia)

Renal Adverse Effects

Acute Kidney Injury (see Acute Kidney Injury)

Acute Interstitial Nephritis (see Acute Interstitial Nephritis)

Hyperkalemia (see Hyperkalemia)

Increased Renal Sodium Reabsorption with Peripheral Edema

Type 4 Renal Tubular Acidosis (RTA) (see Type 4 Renal Tubular Acidosis)


References