Indications

• Hyponatremia (see Hyponatremia, [[Hyponatremia]])

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Pharmacology

• Sodium Chloride (NaCl)

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Administration

• PO: 1-2 g TID
• IV
  • Half Normal Saline (see Half Normal Saline, [[Half Normal Saline]])
  • Normal Saline (see Normal Saline, [[Normal Saline]])
  • Quarter Normal Saline (see Quarter Normal Saline, [[Quarter Normal Saline]])

Dose Adjustment

• Hepatic: none
• Renal:

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Adverse Effects

Cardiovascular Adverse Effects

• Congestive Heart Failure (CHF) (see Congestive Heart Failure, [[Congestive Heart Failure]])

Gastrointestinal Adverse Effects

• Ascites (see Ascites, [[Ascites]])
  • Epidemiology: in the setting of cirrhosis/liver disease

Renal Adverse Effects

• Hypernatremia (see Hypernatremia, [[Hypernatremia]])

Rheumatologic Adverse Effects

• Peripheral Edema (see Peripheral Edema, [[Peripheral Edema]])

Other Adverse Effects

• xxx
• xxx
• xxx

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References

• xxxx