Lumacaftor + Ivacaftor (Orkambi)


Indications

Cystic Fibrosis with Homozygous F508del (Phe508del) Mutation (see Cystic Fibrosis, [[Cystic Fibrosis]])


Pharmacology

Metabolism


Administration

Monitor Liver Function Tests (LFT’s)

Dose Adjustment

Drug Interactions


Adverse Effects

Pulmonary Adverse Effects

Reproductive Adverse Effects

Other Adverse Effects


References