Phosgene Gas

Exposure

  • World War I Wartime Exposure
  • Thermal or Ultraviolet Breakdown Product of Chlorinated Solvents: such as methylene chloride
    • Common exposure from welding metals “degreased” with solvents

Physiology

  • Phosgene Gas Inhalation
    • Phosgene gas is not acutely irritating
    • Low Water Solubility: may result in longer exposure and delayed injury to bronchioles and alveoli

Diagnosis

  • FOB: may be necessary to rule out airway injury

Clinical

(delayed onset of symptoms -> appear 12-24 hrs after exposure)


Treatment

  • Steroids: may be benficial in acute lung injury, but unproven

References

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