Methyl Isocyanate

Epidemiology

  • Involved in Bhopal, India industrial accident

Etiology

  • Pesticide Synthesis

Physiology

  • Methyl Isocyanate Inhalation
    • Respiratory Irritant: no cyanide-mediated mechanism is involved

Clinical

  • Cough (see Cough, [[Cough]])
  • Acute Lung Injury-ARDS (see xxxxx, [[Acute Lung Injury-ARDS]])
    • Pathology: diffuse alveolar damage
  • Reactive Airway Dysfunction Syndrome (see Reactive Airway Dysfunction Syndrome, [[Reactive Airway Dysfunction Syndrome]])

Treatment

  • Steroids: may be benficial in acute lung injury, but are unproven

References

  • xx