Glyphosate

Exposure

  • Herbicide: aka Roundup (Roundup is glyphosate + surfactant)
    • Most commonly used herbicide in the US

Physiology

  • Glyphosate Ingestion
    • Toxicity may be related to the volume of the surfactant component (rather than the type of surfactant)
    • Caustic GI effects

Clinical

GI Manifestations

Pulmonary Manifestations

Cardiovascular Manifestations

Neuro Manifestations

  • Delirium/Coma (see Coma, [[Coma]])
  • Aseptic Meningitis (see Meningitis, [[Meningitis]])

Renal Manifestations


References

  • Acute Poisoning with a Glyphosate-Surfactant Herbicide (‘Roundup’): A Review of 93 Cases. Hum Exp Toxicol January 1991 vol. 10 no. 1 1-8
  • Surfactant volume is an essential element in human toxicity in acute glyphosate herbicide intoxication. December 2011, Vol. 49, No. 10 , Pages 892-899
  • Aseptic meningitis in association with glyphosate-surfactant herbicide poisoning. Clin Toxicol (Phila). 2011 Feb;49(2):118-20