Benign Clear Cell Tumor

(aka Sugar Tumor)

Epidemiology

  • Rare tumor
  • First appears in adulthood

Physiology

  • Benign lung neoplasm

Pathology

  • Polygonal cells with abundant clear, finely-vacuolated cytoplasm (glycogen=sugar tumor)/multinucleated giant cells
  • Immunohistochemical stains are useful to rule out renal cell/primary clear cell carcinoma of lung

Clinical

  • Lung Nodule (see [[Lung Nodule or Mass]]): usually asymptomatic
    • CXR/Chest CT: well-circumscribed, solitary lung nodule (usually <3 cm, but may be as large as 6 cm)

Treatment

  • Surgery: diagnosis usually made at exploratory thoracotomy/autopsy

References

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