Zafirlukast (Accolate)

Adverse Effects

  • Unmasking of Churg-Strauss Syndrome
    • Initiation of zafirlukast and taper of steroids has been reported to result in eosinophilia, asthma, and pulmonary infiltrates c/w Churg-Strauss Syndrome -> it is likely that steroid withdrawal is unmasking this disease, as reinitiation of steroids results in resolution of symptoms

References

  • xxx