Vinblastine

Indications

Hematologic Malignancies

Solid Malignancies

  • xxx

Pharmacology

  • Vinca Plant Alkaloid

Metabolism

  • xx

Administration

  • IV

Dose Adjustment

  • Hepatic
  • Renal

Adverse Effects

Hematologic Adverse Effects

Mild Myelosuppression

Pulmonary Adverse Effects

General Comments

  • Pulmonary toxicity is mainly observed when vinblastine is used in combination with other chemotherapeutic agents, particularly mitomycin-C

Acute Respiratory Distress Syndrome (ARDS) (see Acute Respiratory Distress Syndrome, [[Acute Respiratory Distress Syndrome]])

  • xxxx

Bronchospasm (see Obstructive Lung Disease, [[Obstructive Lung Disease]])

  • xxx

Interstitial Pneumonitis (see Interstitial Lung Disease, [[Interstitial Lung Disease]])

  • xxx

Other Adverse Effects

  • xxx
  • xxx
  • xxx

References

  • xxx