Indications

• Chronic Obstructive Pulmonary Disease (COPD) (see Chronic Obstructive Pulmonary Disease, [[Chronic Obstructive Pulmonary Disease]])
• Note: Tiotropium + Olodaterol is not indicated for the treatment of asthma

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Pharmacology

• Tiotropium (see Tiotropium, [[Tiotropium]])
• Olodaterol (see Olodaterol, [[Olodaterol]])

Metabolism

• xxx

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Administration

• INH

Dose Adjustment

• Hepatic: xxx
• Renal: xxx

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Adverse Effects

Allergic Adverse Effects

• Anaphylaxis (see Anaphylaxis, [[Anaphylaxis]])
• Urticaria-Angioedema (see Urticaria-Angioedema, [[Urticaria-Angioedema]])

Otolaryngologic Adverse Effects

• Nasopharyngitis: occurs in 12.4% of cases

Pulmonary Adverse Effects

• Cough (see Cough, [[Cough]]): occurs in 3.9% of cases
• Paradoxical Bronchospasm (see Obstructive Lung Disease, [[Obstructive Lung Disease]])

Other Adverse Effects

• Back Pain (see Back Pain, [[Back Pain]]): occurs in 3.6% of cases

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References

• xxx