Teniposide (Vumon, VM-26)

Indications


Pharmacology

  • Podophyllotoxin Agent: inhibition of type II topoisomerase
    • Dose-dependent single and double-stranded DNA breaks in DNA and DNA-protein cross-links
    • Teniposide does not intercalate into DNA or bind avidly to DNA

Adverse Effects

Pulmonary Adverse Effects

  • Hypersensitivity Reaction

References

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