Temsirolimus

Indications

  • Endometrial Cancer (see Uterine Cancer, [[Uterine Cancer]])
  • Breast Cancer (see Breast Cancer, [[Breast Cancer]])
  • Neuroendocrine Tumors
  • Advanced Renal Cell Carcinoma (see Renal Cancer, [[Renal Cancer]])

Pharmacology


Administration

  • xxxx

Adverse Effects

Pulmonary Adverse Effects

General Comments

  • 36% of cases develop pulmonary toxicity, only half of which are symptomatic

Interstitial Pneumonitis (see Interstitial Lung Disease, [[Interstitial Lung Disease]])

  • Diagnosis: ground-glass infiltrates
  • Treatment: discontinuation of temsirolimus

Pneumonia-Like Picture (see Pneumonia, [[Pneumonia]])

  • Diagnosis: alveolar infiltrates
  • Treatment: discontinuation of temsirolimus

References

  • xxx