Simvastatin (Zocor)

Pharmacology

  • Synthetic derivate of a fermentation product of Aspergillus terreus
  • HMG-CoA reductase inhibitor

Adverse Effects


References

  • Statin-induced fibrotic nonspecific interstitial pneumonia. ERJ March 1, 2002 vol. 19 no. 3 577-580
  • Eosinophilic pleurisy caused by simvastatin. Rassegna di Patolgia del\’Apparato Respiratorio 2008; 23: 1-3
  • Polymyalgia, hypersensitivity pneumonitis and other reactions in patients receiving HMG-CoA reductase inhibitors. Chest 1999; 115: 886-889
  • Simvastatin-induced lupus erythematosus. Southern Medical Journal 1998; 91: 873-874
  • Interstitial lung disease with pleural effusion caused by simvastin. J Intern Med 1996; 239: 361-363
  • Dermatomyositis with lung involvement in a patient treated with simvastatin. Aust NZ J Med 1995; 25: 745-746
  • Idiopathic bronchiolitis obliterans with organizing pneumonia. An acute and life-threatening syndrome. Chest 1995; 108: 271-277
  • Lupuslike syndrome associated with simvastatin. Arch Intern Med 1992; 152: 1093-1094