Rifabutin

Indications

  • xxx

Pharmacology

  • Rifamycin Group Antibiotic: inhibits bacterial DNA-dependent RNA polymerase -> inhibits bacterial RNA synthesis
    • Rifamycins (a subclass of the ansamycins) are produced by the bacterium Amycolatopsis Rifamycinica (originally named Streptomyces Mediterranei when it was first isolated in 1957) or synthesized
    • Rifamycins were originally named after the French crime story Rififi (which was favored the researchers who discovered these agents)
    • Members of Rifamycin Group
      • Rifamycins
      • Rifabutin
      • Rifalazil
      • Rifampin (Rifampicin) (see Rifampin, [[Rifampin]])
      • Rifapentine

Administration

  • PO: xxx

Adverse Effects

  • xxx

References

  • xxx