Indications

• Malaria (see Malaria, [[Malaria]])

---

Pharmacology

• xxx

Dose Adjustment

• Hepatic
• Renal

---

Adverse Effects

Cardiovascular Adverse Effects

• QT Prolongation/Torsade (see Torsade, [[Torsade]]): definite association with torsade

Gastrointestinal Adverse Effects

• Asymptomatic Elevation of Hepatic Transaminases (Isolated Transaminitis) (see Drug-Induced Hepatotoxicity, [[Drug-Induced Hepatotoxicity]])

Hematologic Manifestations

• Drug-Induced Autoimmune Hemolytic Anemia (see Hemolytic Anemia, [[Hemolytic Anemia]])

Rheumatologic Adverse Effects

• Drug-Induced Systemic Lupus Erythematosus (SLE) (see Systemic Lupus Erythematosus, [[Systemic Lupus Erythematosus]])
  • Epidemiology: moderate-low risk of developing drug-induced SLE

---

References

• xxx