Quinidine (Quinaglute, Quinidex)

Indications

  • Malaria (see Malaria, [[Malaria]])

Pharmacology

  • xxx

Dose Adjustment

  • Hepatic
  • Renal

Adverse Effects

Cardiovascular Adverse Effects

  • QT Prolongation/Torsade (see Torsade, [[Torsade]]): definite association with torsade

Gastrointestinal Adverse Effects

  • Asymptomatic Elevation of Hepatic Transaminases (Isolated Transaminitis) (see Drug-Induced Hepatotoxicity, [[Drug-Induced Hepatotoxicity]])

Hematologic Manifestations

  • Drug-Induced Autoimmune Hemolytic Anemia (see Hemolytic Anemia, [[Hemolytic Anemia]])

Rheumatologic Adverse Effects

  • Drug-Induced Systemic Lupus Erythematosus (SLE) (see Systemic Lupus Erythematosus, [[Systemic Lupus Erythematosus]])
    • Epidemiology: moderate-low risk of developing drug-induced SLE

References

  • xxx