Glucarpidase (Voraxaze)

Indications

  • Methotrexate Toxicity in the Setting of Renal Failure (see Methotrexate, [[Methotrexate]])

Pharmacology

  • Enzyme Which Inactivates Methotrexate (see Methotrexate, [[Methotrexate]])

Metabolism

  • xxxx

Administration

  • xxxx

Dose Adjustment

  • Hepatic:
  • Renal:

Adverse Effects

Other Adverse Effects

  • xxx
  • xxx
  • xxx

References

  • Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma.  Leuk Lymphoma.  2012;53:1867–1875 [MEDLINE]