Deferasirox (Exjade)

Indications

  • Iron Overload (see Iron Overload, [[Iron Overload]])
    • FDA-approved for this indication since 2005

Pharmacology

  • Iron Chelation

Administration

  • PO: 20-30 mg/kg/day (once daily) dissolved in 8 ounces of water or juice
    • Take on an empty stomach (1 hr before or 2 hrs after meal)
    • Annual Cost (20 mg/kg/day for 60 kg adult): $39,000
    • Annual Cost (30 mg/kg/day for 60 kg adult): $58,500

Adverse Effects

Gastrointestinal Adverse Effects

Hematologic Adverse Effects

Renal Adverse Effects

Other Adverse Effects

  • Gritty Taste

References

  • xxx