Conivaptan (Vaprisol)

Indications


Contraindications

  • Need to Correct Na Rapidly
  • xxx

Pharmacology

  • Aquaretic: water loss
    • This effect is usually partially offset by patient’s own fluid intake

Dosage/Administration

  • Start (In Hospital):
  • After At least 24 Hrs, Titrate Up To:

Adverse Effects

Neurologic Adverse Effects

  • Central Pontine Myelinolysis (see Central Pontine Myelinolysis, [[Central Pontine Myelinolysis]]): associated with excessively rapid correction of serum sodium (>12 mEq/L per 24 hrs)
  • Hypernatremia (see Hypernatremia, [[Hypernatremia]])
  • Thirst

Other Adverse Effects

  • xxx

References

  • xxx