Caspofungin (Cancidas)

Indications

  • Candida (see Candida, [[Candida]])

Pharmacology

  • Inhibits Formation of ß-Glucans in Fungal Cell Wall: ß-Glucans are not present in the mammalian cell wall
    • Candida (see Candida, [[Candida]]): cidal for all species
    • Aspergillus (see Aspergillus, [[Aspergillus]]): probably also cidal for all species
    • Cryptococcus (see Cryptococcus, [[Cryptococcus]]): not active

Administration

  • IV:

Adverse Effects

Gastroenterologic Adverse Effects

  • Elevated LFT’s

Other Adverse Effects

  • Flushing: with rapid infusion
  • Rash

References

  • xxx