Apremilast (Otezla)

Indications


Pharmacology

  • Phosphodiesterase Type 4 Inhibitor (PDE4 Inhibitor) (see Phosphodiesterase Type 4 Inhibitors, [[Phosphodiesterase Type 4 Inhibitors]])
    • Phosphodiesterase Type 4 is the Predominant cAMP-Metabolizing Enzyme Found in Inflammatory/Immune Cells: this explains the anti-inflammatory properties of these agents

Metabolism

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Administration

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Dose Adjustment

  • Hepatic:
  • Renal:

Adverse Effects

Other Adverse Effects

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References

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