β-Lactam Antibiotics

Agents

Penicillins (see Penicillins, [[Penicillins]])

Natural Penicillins

  • Benzathine Penicillin
  • Penicillin G (Benzylpenicillin) (see Penicillin G, [[Penicillin G]])
  • Penicillin V
  • Procaine Penicillin

Penicillinase-Resistant Penicillins

Aminopenicillins

  • General Comments
    • Vulnerable to inactivation by β-lactamases
  • Amoxacillin (see Amoxacillin, [[Amoxacillin]]): due to potential inactivation by β-lactamases, usually used in a formulation with a β-lactamase inhibitor (like clavulanic acid)
  • Ampicillin (see Ampicillin, [[Ampicillin]]): due to potential inactivation by β-lactamases, usually used in a formulation with a β-lactamase inhibitor (like sulbactam)
  • Bacampicillin

Extended-Spectrum/Anti-Pseudomonal Penicillins

  • General Comments
    • Have activity against many gram-negative organisms of the Enterobacteriaceae family (including Pseudomonas aeruginosa)
    • Vulnerable to inactivation by β-lactamases
  • Acylaminopenicillins
    • Azlocillin
    • Mezlocillin
    • Piperacillin: due to potential inactivation by β-lactamases, usually used in a formulation with a β-lactamase inhibitor (like tazobactam)
  • Alpha-Carboxypenicillins
    • Carbenicillin
    • Ticarcillin: due to potential inactivation by β-lactamases, usually used in a formulation with a β-lactamase inhibitor (like clavulanic acid)

Cephalosporins (see Cephalosporins, [[Cephalosporins]])

First Generation

  • Cefadroxil (Duricef) (see Cefadroxil, [[Cefadroxil]])
  • Cefazolin (Ancef, Kefzol) (see Cefazolin, [[Cefazolin]])
  • Cephalexin (Keflex) (see Cephalexin, [[Cephalexin]])
  • Cephradrine (Velosef) (see Cephradrine, [[Cephradrine]])

Second Generation

  • Cefaclor (Ceclor, Raniclor) (see Cefaclor, [[Cefaclor]])
  • Cefotetan (Cefotan) (see Cefotetan, [[Cefotetan]])
  • Cefotiam (see Cefotiam, [[Cefotiam]])
  • Cefoxitin (Mefoxin) (see Cefoxitin, [[Cefoxitin]])
  • Cefprozil (Cefzil) (see Cefprozil, [[Cefprozil]])
  • Cefuroxime (Zinacef, Ceftin) (see Cefuroxime, [[Cefuroxime]])
  • Loracarbef (Lorabid) (see Loracarbef, [[Loracarbef]])

Third Generation

  • Cefdinir (Omnicef) (see Cefdinir, [[Cefdinir]])
  • Cefditoren (Sprectacef) (see Cefditoren, [[Cefditoren]])
  • Cefixime (Suprax) (see Cefixime, [[Cefixime]])
  • Cefoperazone (Cefobid) (see Cefoperazone, [[Cefoperazone]])
  • Cefotaxime (Claforan) (see Cefotaxime, [[Cefotaxime]])
  • Cefpodoxime (Vantin) (see Cefpodoxime, [[Cefpodoxime]])
  • Ceftazidime (Fortaz, Tazicef, Ceptaz) (see Ceftazidime, [[Ceftazidime]])
  • Ceftibuten (Cedax) (see Ceftibuten, [[Ceftibuten]])
  • Ceftizoxime (Cefizox) (see Ceftizoxime, [[Ceftizoxime]])
  • Ceftriaxone (see Ceftriaxone, [[Ceftriaxone]])

Fourth Generation

  • Cefepime (Maxipime) (see Cefepime, [[Cefepime]])

Fifth Generation

  • Ceftaroline (Teflaro, Zinfloro) (see Ceftaroline, [[Ceftaroline]])
  • Ceftobiprole (Zeftera, Zevtera) (see Ceftobiprole, [[Ceftobiprole]])

Carbapenems (see Carbapenems, [[Carbapenems]])


References

  • xxx